Ommended after the first trimester for patients with CD4 + cell counts less than 50 106 per L ; .35 Azithromycin per mm3 50 dihydrate Zithromax ; is the drug of choice because of its safety profile. Additional preventative care should include an annual influenza immunization and pneumococcal immunization every five years.35 Pregnant patients with recurrent or active tuberculosis, toxoplasmosis, cryptococcal disease, histoplasmosis, coccidioidomycosis or cytomegalovirus disease should be treated similarly to nonpregnant patients considering the lifethreatening risks to maternal health.35 Final Comment Care for pregnant patients infected with HIV is rapidly evolving with multiple interventions causing a decrease in vertical transmission rates of HIV infection Table 6 ; and and furosemide.
The cash, cash equivalents and available for sale securities were due on demand or within one year. A 10% change in average interest rate would have had an approximate ##TEXT##.3 million impact on interest income. Most of our transactions are conducted in U.S. dollars. We do have certain agreements with parties located outside the United States. Transactions under certain of these agreements are conducted in U.S. dollars, subject to adjustment based on significant fluctuations in currency exchange rates. Transactions under certain other of these agreements are conducted in the local foreign currency. If the applicable exchange rate undergoes a change of 10.0%, we do not believe that it would have a material impact on our results of operations or cash flows. Item 8. Financial Statements and Supplementary Data.

ATTACHMENT 4.3 --continued-- on their PDL, except for Evista which was listed as hormone replacement. Mr. Keeley replied that he classified drugs based on Fact and Comparison's major subheadings. He stated he would look for that. Ms. Perry asked about an emergency fill procedure. Mr. Keeley answered that they had a 72-hour fill policy and Ohio did about 350 emergency fills per month. Board Action: The Board approved The CareSource Preferred Drug List. Mr. Barth then introduced Benjamin Schatzman, corporate pharmacy director with Molina Health Care. They used PDLs that were customized for each state, overseen by their own Pharmacy and Therapeutics Committees which met quarterly to review literature and update the PDLs. He stated that quantity limits and prior authorization requirements were made comparable to what other MCOs in Indiana were doing. He added that drug not on the list required prior authorization. Ms. Perry asked what the term "package C numbers" meant and why OTCs were excluded. Ms. Schatzman replied that it referred to the CHIP Program, that traditionally across the country OTCs were not part of that benefit. Dr. Mychaskiw asked for clarification on how Molina handled the prior authorization requests. Mr. Schatzman answered that Molina used a pharmacy benefit manager for electronic claims processing with a help desk that was open 24-hours a day. Prior authorizations were handled onsite by the plan via fax during business hours. Their plan allowed an emergency 72-hour supply to be dispensed after hours, with approval granted later during business hours, for online adjudication. Dr. Wernert asked why all second-generation antipsychotics and acetyl cholinesterase inhibitors for dementia required prior authorization. Mr. Schatzman replied that the concern was to insure the antipsychotics were used for FDA-approved indications consistent with the manufacturer's labeling or peer-reviewed medical literature for off-label uses. Mr. Wilson asked if physicians were required to give the journal citation when requesting approval for off-label use of an agent. Would someone then go and read the article? He asked if they did not keep up with the literature themselves. Mr. Schatzman said they did their best to keep up with the literature, and would build it into their prior authorization criteria any time the literature recognized an off-label use as a commonly accepted practice. Dr. Ceh asked if Molina had the ability to tag claims by prescriber specialty to pay for certain criteria. Mr. Schatzman answered that as they built their provider network in terms of certain subspecialties, they had the ability to create a list of network physicians by DEA number that would allow prescriptions to adjudicate for specific criteria. Dr. Ceh stated she had a problem with the macrolide antibiotics having only erythromycin on the PDL, forcing everybody to take erythromycin base first. Mr. Schatzman replied it was due to over-utilization of Z-Pak as a firstline agent that Zithromax and Biaxin were not on the list. They encouraged the use of other antibiotics, such as amoxicillin or penicillin as well as erythromycin, as first-line choices based on the disease being treated. When questioned about penicillin allergies, he responded that they had a nationwide policy of responding to requests within one business day. Antibiotic got top priority and clonidine.
In disease from use of influenza virus vaccine in patients who have chronic bronchitis exclusively Griffith, 1993 ; . However, one nursing.
Talized severelyepressed d patient hould s begiven thesmallest drugamount . f sible.Inschizophrenic patients, activation fthepsychosis o mayoccur andrequire reductionfdosage rtheaddition majorranquilizer o o ofa t tothemedication schedule. Manic orhypomanic episodes ayoccur, specially patients m e in with cyclic-typeisorders; d Surmontil mayhave bediscontinued to untiltheepisode is relieved ndreinstituted, required, lower osage. a it at Umitconcurrent adminis tration ofSurmontil andelectroconvulsive therapy tothosepatients forwhom is it and avalide. NDA 50-733 S-005 Page 15 Azithromycin given by the oral route did not affect the prothrombin time response to a single dose of warfarin. However, prudent medical practice dictates careful monitoring of prothrombin time in all patients treated with azithromycin and warfarin concomitantly. Concurrent use of macrolides and warfarin in clinical practice has been associated with increased anticoagulant effects. The following drug interactions have not been reported in clinical trials with azithromycin; however, no specific drug interaction studies have been performed to evaluate potential drug-drug interaction. Nonetheless, they have been observed with macrolide products. Until further data are developed regarding drug interactions when azithromycin and these drugs are used concomitantly, careful monitoring of patients is advised: Digoxin - elevated digoxin levels. Ergotamine or dihydroergotamine - acute ergot toxicity characterized by severe peripheral vasospasm and dysesthesia. Triazolam - Increased pharmacologic effect of triazolam by decreasing the clearance of triazolam. Drugs metabolized by the cytochrome P450 system - elevations of serum carbamazepine, terfenadine, cyclosporine, hexobarbital, and phenytoin levels. Laboratory Test Interactions: There are no reported laboratory test interactions. Carcinogenesis, Mutagenesis, Impairment of Fertility: Long-term studies in animals have not been performed to evaluate carcinogenic potential. Azithromycin has shown no mutagenic potential in standard laboratory tests: mouse lymphoma assay, human lymphocyte clastogenic assay, and mouse bone marrow clastogenic assay. No evidence of impaired fertility due to azithromycin was found. Pregnancy: Teratogenic Effects. Pregnancy Category B: Reproduction studies have been performed in rats and mice at doses up to moderately maternally toxic dose levels i.e., 200 mg kg day by the oral route ; . These doses, based on a mg m2 basis, are estimated to be 4 and 2 times, respectively, the human daily dose of 500 mg by the oral route. In the animal studies, no evidence of harm to the fetus due to azithromycin was found. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, azithromycin should be used during pregnancy only if clearly needed. Nursing Mothers: It is not known whether azithromycin is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when azithromycin is administered to a nursing woman. Pediatric Use: Safety and effectiveness of azithromycin for injection in children or adolescents under 16 years have not been established. In controlled clinical studies, azithromycin has been administered to pediatric patients age 6 months to 16 years ; by the oral route. For information regarding the use of ZITHROMAX azithromycin for oral suspension ; in the treatment of pediatric patients, refer to the INDICATIONS AND USAGE and DOSAGE AND ADMINISTRATION sections of the prescribing information for ZITHROMAX azithromycin for oral suspension ; 100. Seiler raised her price target to from after VXGN resolved issues associated with warrants issued in 2001. Seiler said the new agreement eliminates monthly penalty payments of 0, 000-0, 000 and additional cash outlays of at least .9M. VXGN closed Friday at .41, up ##TEXT##.65 on the week. Vertex VRTX ; SunTrust David Witzke New Neutral and hydrochlorothiazide.

REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM To the Board of Directors and Stockholders of Anadys Pharmaceuticals, Inc. We have audited the accompanying consolidated balance sheets of Anadys Pharmaceuticals, Inc. as of December 31, 2004 and 2003, and the related consolidated statements of operations, stockholders' equity deficit ; and cash flows for each of the three years in the period ended December 31, 2004. These financial statements are the responsibility of the Company's management. Our responsibility is to express an opinion on these financial statements based on our audits. We conducted our audits in accordance with the standards of the Public Company Accounting Oversight Board United States ; . Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. We were not engaged to perform an audit of the Company's internal controls over financial reporting. Our audit included consideration of internal control over financial reporting as a basis for designing audit procedures that are appropriate in the circumstances, but not for the purpose of expressing an option of the effectiveness of the Company's internal control over financial reporting. Accordingly we express no such option. An audit also includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements, assessing the accounting principles used and significant estimates made by management, and evaluating the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion. In our opinion, the financial statements referred to above present fairly, in all material respects, the consolidated financial position of Anadys Pharmaceuticals, Inc. at December 31, 2004 and 2003 and the consolidated results of its operations and its cash flows for each of the three years in the period ended December, 31, 2004, in conformity with U. S. generally accepted accounting principals. s Ernst & Young LLP San Diego, California February 9, 2005. In September, 1991, the Office of Generic Drugs startedimplementation of its Application Integrity Policy by suspendingreview of applications suspectedof being tainted by fraud. Review statusfigures reported sincethis date eXc!ude-suspended applications. Asof December31, 1999, 1 original appljcation and 18 supplementswere suspended. Upon completion ofvalidity assessments, suspended applications may be returned to active pending status and doxazosin. From adult bone marrow can inhibit T-cell alloreactivity in vitro. Dr. Frassoni, from the San Martino Hospital in Genoa, Italy, described results from a European Group for Blood and Marrow Transplantation EBMT ; study of 40 patients with grade III-IV acute GVHD who were resistant to second-line GVHD therapy. Patients in this study were infused with mesenchymal stromal cells obtained from HLA-identical sibling donors n 5 ; , haploidentical donors n 19 ; and unrelated HLA-mismatched donors n 41 ; . Median cell dose was 1.0 x 106 cells kg recipient body weight range 0.4-9 ; . Patients received one dose n 19 ; , two doses n 19 ; , three doses n 1 ; or five doses n 1 ; of mesenchymal stromal cells. Nineteen patients had complete responses, nine had incomplete responses and seven did not respond. Nine patients developed extensive chronic GVHD. Twenty-one of the 40 patients 52.5% ; are alive at six weeks to 3.5 years post-transplant and showed evidence that the infused mesenchymal stromal cells repaired tissues in the gut, liver, and skin damaged by GVHD. However, the optimal strategy for treating GVHD with mesenchymal stromal cells is not yet known, according to Dr. Frassoni, although it's clear that they do have tissuerepairing effects and should therefore be tested in randomized clinical trials.3 In a poster presentation, Dr. Partow Kebriaei reported results from a phase II study of mesenchymal stromal cells in combination with steroids used to treat 31 patients who developed acute GVHD after related or unrelated donor hematopoietic cell transplantation. Dr. Kebriaei, from the M.D. Anderson Cancer Center, reported that 21 of the 31 patients achieved a complete response no evidence of GVHD ; and seven patients achieved a partial response with an improvement in one or more affected organs. All of the patients initially diagnosed with GVHD of the skin had a response, and 83% of the patients with gastrointestinal GVHD had a response.4.

DISCLAIMER: Please note that azithromycin Zithromax ; is unlicensed for cats in the UK, and that although it is used in other countries for cats, the UK has not approved any dosage yet, so the responsibility for using it at any dose is at the owners own risk and I cannot accept any responsibility for its usage or dosage. As always, please be advised by your vet and betapace and Buy cheap zithromax. Aim: Some patients with epilepsy are affected by acute repetitive or serial seizures that last several minutes or hours. Benzodiazepines are the drugs of choice for the treatment of acute repetitive seizures. They are safe and the results are instantaneous. However, oral administration is often difficult in a patient who is actively convulsing. The purpose of this study is to assess the effectiveness of teaching home administration of rectal diazepam for acute repetitive seizures by the paediatric epilepsy nurse to caregivers, and the efficacy of the rectal diazepam administrated. Methods: This prospective study included 127 patients aged 0 to 15 years old who had epileptic seizures or febrile seizures from March 2006 to May 2007. Caregivers were taught how to identify repetitive seizures, administer diazepam rectally and monitor respiration, seizure activity and adverse events. Of the 127 patients, those who were readmitted to children's emergency at National University Hospital were recruited into the study. Results: Twenty-five patients were reviewed at the children's emergency for seizure recurrence, 22 of them 88% ; had rectal diazepam administered at home and 3 of them 12% ; did not receive it as the seizure stopped spontaneously within 5 minutes. Of the 22 patients who had rectal diazepam, the seizure stopped after the administration of rectal diazepam in 16 of them 72% 6 of the patients 27% ; required further intravenous treatment in the emergency room or after admission to the hospital. Conclusion: The education provided by the paediatric epilepsy nurse on home administration of rectal diazepam is effective. Rectal diazepam is safe and effective for acute repetitive seizures and can be administered by caregivers who are trained. It is also a reassuring safety net for patients who are prone to status epilepticus and who travel or live far away from a hospital. NUR 013 Burning Platform for Change: A CQI Approach to Improve the Continuous Ambulatory Peritoneal Dialysis CAPD ; Programme in a Tertiary Teaching University Hospital. Private outpatient alcoholism treatment center va outpatient center drug-free outcome more likely with methadone treatment and benicar.
ANNEXURE J NATIONAL PROSECUTING AUTHORITY APPLICATIONS : : : Please forward your application, quoting reference number to: The Document Centre, Private Bag X752, Pretoria, 0001, All Electronic applications emails ; must be in MS Word format. 05 March 2007 Application must be accompanied by a Z83 obtained from any Public Service Department or on an internet at gov.za and a Recent updated comprehensive CV as well as a certificated copies of all Qualification s ; . Applications received after the closing date will not be considered. The appointee will be subjected to security Vetting. OTHER POSTS POST 07 90 SALARY CENTRE REQUIREMENTS : : : DEPUTY MANAGER IMU ; R146 685 per annum plus housing allowance, annual service bonus, pension and medical benefits Pretoria A recognised Bachelor's degree or equivalent qualification. Proven experience in case management. Experience in Report writing. The successful candidate will be required to sign a performance agreement contract. Good written and oral communication skills. Analytical and investigative skills. Proven ability to work under stressful environment. Problem shooting abilities. Knowledge and understanding of the regulatory framework for the Public Service e.g .Public Finance Management Act, Treasury Regulations and Public Service Act and regulations as well as NPS Act ; . Project management. General Computer literacy skills and knowledge in programmes such as MS Word, PowerPoint, Excel, etc. Setting up processes, which screens and or prioritise requests documents from IMU management or other Units. Managing the integrated Case Management and referral system in line with minimum information security requirements, financial declaration, and labour relations. Evaluate information and case and provide timely reports to IMU management and other stakeholders when required. Conduct research on the management of case management system to inform policy development. Managing the auxiliary services of the Unit including document management and record keeping. Managing specific projects initiatives within the IMU. Provide expert advice to IMU management on case management issues. Recruit0533 npa.gov.za Fax no 012 843 4369 ASSISTANT MANAGER: GENERAL SCCU ; R122 841 per annum, plus housing subsidy, pension and medical aid benefits Port Elizabeth 1 ; , Durban 1 ; Three year degree or diploma and more than 3 years relevant experience. Performing general administrative functions. Proven managerial experience. Problem solving skills. Knowledge and skill of administrative and secretarial services. General computer literacy skills and knowledge in programs such as MS Word, Powerpoint, Excel, etc. Strong interpersonal and communication skills. Provide administrative support to the office, logistical support and human resources administrative. Keep a well-organized administrative system for the office. Liaise with Corporate Service on all matters pertaining to administrative functions of the office. Draft correspondence to members of the public, other organizations and state departments. Manage sub-ordinates. Handle other administrative duties of the Unit Recruit0534 npa.gov.za Fax no 012 843 4370 ASSISTANT MANAGER: FINANCE: SALARIES R122 841 plus housing subsidy, pension and medical benefits Pretoria Candidates must be in possession of a Grade 12 Certificate with at least six years experience in the salaries section in the Public sector, or a Degree Diploma in Financial Management with three years experience in the.
Dailymed: about dailymed zithromax azithromycin for injection ; is supplied in lyophilized form in a.
Neutron Particles Neutrons are particles normally contained in the nucleus of an atom. They can be released through certain manufacturing processes, such as nuclear fission splitting an atomic nucleus ; . Neutrons are considerably larger than beta particles but have only one-fourth the mass of alpha particles. Because they can penetrate even thick lead shields, they can be extremely damaging to humans. However, neutron radiation is very rare since it is generally emitted only when atomic weapons are detonated. LIMITING EXPOSURE You can minimize your exposure to any type of radiation by: 1. Limiting the time that you are near the source of radiation 2. Increasing the distance between yourself and the source 3. Shielding yourself with appropriate protective clothing Time The shorter the time you are exposed to radiation, the less your exposure. Work quickly and efficiently; rotate teams to keep individual exposures to a minimum. Distance The farther you are from a source of radiation, the lower the dose you receive. If you must approach low level radioactive materials, do not touch them; use shovels or brooms and avoid physical contact. Shielding SCBA and bunker gear shields you from most alpha and beta radiation. Several inches of lead are necessary to shield you from gamma radiation. If possible, use clothing, vehicles, equipment, containers or natural barriers like hills, trees, and rocks to protect yourself from radiation exposure. However, be aware that your apparatus, depending on its profile and construction material, may not provide adequate shielding. Shielding also includes covering the source itself. For example, you may be able to prevent exposure to alpha and some beta radiation if you cover the source with a drum or heavy material, such as a tarp. Like other exposures, if your clothing or skin is contaminated with a radioactive substance, exposure will continue until you are decontaminated. MEDICAL TREATMENT Potassium iodide KI ; , if taken in time, blocks the thyroid gland's uptake of radioactive iodine and thus could help prevent thyroid cancers and other diseases that might otherwise be caused by exposure to airborne radioactive iodine that could be dispersed in a nuclear accident. KI provides protection only for the thyroid from 8-21.
3.1. Human data.50 3.1.1. Exposure during prenatal development .50 3.1.2. Exposure during breast feeding .72 3.1.3. Exposure during childhood.74 3.2. Experimental animal data.77 3.2.1. Prenatal developmental studies .77 3.2.2. Postnatal developmental studies.91 3.2.3. In vitro or mechanistic studies .95 3.3 Summary of Developmental Toxicity .97 3.3.1 Human Data .97 3.3.2. Experimental animal data .100 4. Reproductive toxicity data .103 4.1. Human data.103 4.1.1. Effects on menstruation ovulation .103 4.1.2. Galactorrhea.104 4.1.3. Male reproductive effects.104 4.1.4. Sexual dysfunction .105 4.2. Experimental animal reproduction .116 4.2.1. Female reproduction.116 4.2.2. Male reproduction .122 4.2.2.1. In vivo.122 4.2.3. Fertility Reproductive function .133 4.3 Summary of reproductive toxicity data .134 4.3.1 Human data .134 4.3.2 Experimental animal data .135 5. 5.1. Summaries, conclusions, and critical data needs .136 Summary and conclusions of reproductive and developmental hazards .136 Summary of human exposure .136 Overall conclusions .136 Critical Data Needs .136 References .137 Data tables .147.

ANTIRETROVIRALS NRTIs- abacavir Ziagen ; , abacavir lamivudine Epzicom ; , abacavir lamivudine zidovudine Trizivir ; , didanosine ddI, Videx ; , emtricitabine Emtriva ; , lamivudine Epivir, 3TC ; , lamivudine zidovudine Combivir ; , stavudine d4T, Zerit ; , tenofovir Viread ; , tenofovir emtricitabine Truvada ; , zalcitabine ddC, Hivid ; , zidovudine AZT, Retrovir ; . PIs- amprenavir Agenerase ; , atazanavir Reyataz ; , fosamprenavir Lexiva ; , indinavir Crixivan ; , lopinavir ritonavir Kaletra ; , nelfinavir Viracept ; , ritonavir Norvir ; , saquinavir Fortovase, Invirase ; , tipranavir Aptivus ; . NNRTIsdelavirdine Rescriptor ; , efavirenz Sustiva ; , nevirapine Viramune ; . Entry Inhibitors- enfuvirtide Fuzeon ; . OI DRUGS PHS "A1 OI"s- acyclovir Zovirax ; , amphotericin B, azithromycin Zithromax ; , clarithromycin Biaxin ; , clindamycin Cleocin ; , famciclovir Famvir ; , fluconazole Diflucan ; , foscarnet Foscavir ; , ganciclovir Cytovene ; , itraconazole Sporonox ; , leucovorin calcium, pentamidine Nebupent, Pentam ; , pyrimethamine Daraprim ; , rifabutin Mycobutin ; , sulfadiazine, TMP SMX Bactrim, Septra ; , valacyclovir Valtrex ; , valganciclovir Valcyte ; . Other OIs- amikacin Amikin ; , atovaquone Mepron ; , ciprofloxacin Cipro ; , clotrimazole Mycelex ; , dapsone, erythropoietin Epogen ; , ethambutol Myambutol ; , ketoconazole Nizoral ; , metronidazole Flagyl ; , nystatin Mycostatin ; , primaquine, trimethoprim Proloprim ; , TREATMENTS FOR METABOLIC DISORDERS Diabetic- metformin Glucophage ; . Hyperlipidemia- atorvastatin Lipitor ; , fenofibrate Tricor Lofibra ; , pravastatin Pravachol ; , rosuvastatin Crestor ; . Wasting- Megestrol Megace ; . Vaccines- Enterix-B HBV ; , Haverix HAV ; , Twinrix HAV and HBV ; . ALL OTHERS Prenatal-S, sertraline Zoloft ; , voriconazole Vfend ; . Removed in 2005- Centrum Silver, Cerovite Silver, clofazimine Lamprene ; , filgrastim G-CSF, Neupogen ; , gemfibrozil Lopid ; , hydroxyurea Hydrea ; , Nizoral Cream, Tegrin Shampoo, contraceptives condoms with without nonoxynol 9, Spermicidal Foam, VCF Spermicidal Film, Depo-Provera, Norplant, Ovulation thermometer, Fertility Awareness book, charts, videotape"All Methods" counseling pamphlet, Oral Contraceptives, Loestrin Fe, Micronor, Nordette, Ortho-Cyclen, Ortho Novum, Triphasil. Patients with cystic fibrosis, patients with nosocomially acquired infections, patients with known or suspected bacteremia, patients requiring hospitalization, elderly or debilitated patients, or patients with significant underlying health problems that may compromise their ability to respond to their illness including immunodeficiency or functional asplenia ; . Pharyngitis tonsillitis caused by Streptococcus pyogenes as an alternative to first-line therapy in individuals who cannot use first-line therapy. NOTE: Penicillin by the intramuscular route is the usual drug of choice in the treatment of Streptococcus pyogenes infection and the prophylaxis of rheumatic fever. ZITHROMAX is often effective in the eradication of susceptible strains of Streptococcus pyogenes from the nasopharynx. Because some strains are resistant to ZITHROMAX, susceptibility tests should be performed when patients are treated with ZITHROMAX. Data establishing efficacy of azithromycin in subsequent prevention of rheumatic fever are not available. Uncomplicated skin and skin structure infections due to Staphylococcus aureus, Streptococcus pyogenes, or Streptococcus agalactiae. Abscesses usually require surgical drainage. Urethritis and cervicitis due to Chlamydia trachomatis or Neisseria gonorrhoeae. Genital ulcer disease in men due to Haemophilus ducreyi chancroid ; . Due to the small number of women included in clinical trials, the efficacy of azithromycin in the treatment of chancroid in women has not been established. ZITHROMAX, at the recommended dose, should not be relied upon to treat syphilis. Antimicrobial agents used in high doses for short periods of time to treat non-gonococcal urethritis may mask or delay the symptoms of incubating syphilis. All patients with sexually-transmitted urethritis or cervicitis should have a serologic test for syphilis and appropriate cultures for gonorrhea performed at the time of diagnosis. Appropriate antimicrobial therapy and follow-up tests for these diseases should be initiated if infection is confirmed. Appropriate culture and susceptibility tests should be performed before treatment to determine the causative organism and its susceptibility to azithromycin. Therapy with ZITHROMAX may be initiated before results of these tests are known; once the results become available, antimicrobial therapy should be adjusted accordingly. To reduce the development of drug-resistant bacteria and maintain the effectiveness of ZITHROMAX azithromycin ; and other antibacterial drugs, ZITHROMAX azithromycin ; should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

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